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28th October 2010 Medicore Issue 11 September/October 2010

Topics

Guest Editorial
Diabetes
Gastroenterology
Psychiatry
Dermatology
Palliative Care
Emerging Uses of FDA-Approved Drugs
Emerging uses of EMEA-Approved Drugs
World Health Matters
The BIG FOUR Journals
View from The Waiting Room

In this Issue

New and emerging therapies in Type 2 diabetes
Pioglitazone plus exenatide brings more benefit to patients
Hopes grow for artificial pancreas
IBD - Chemokine Inhibitor shows promise
Modest result for new monoclonal antibody
Clear take-home messages from ECNP
Catching multiple sclerosis before it strikes
UV-B treatment may improve psoriasis and vitamin D levels
Women who drink beer more likely to develop psoriasis
Inadequate access to opioid-based pain relief is a human rights issue for cancer patients
Statin therapy related to reduction in cancer recurrence following prostatectomy
Unapproved use of quinine sulfate gets FDA warning
Naltrexone and Bupropion for lowering bodyweight
Ketamine in quick relief of depression in treatment-resistant bipolar disorder
EU-US collaboration on confidentiality
Privatising alcohol sales ‘will spark violence’
Function found for Alzheimer’s protein
Research links Huntingtin to Neurogenesis
Heart attacks jump in young Italian women
Icatibant shows promise for treating hereditary Angioedema
Rosiglitazone treatment shows increase in CV risks and death
Study shows promise for Hepatitis-E Vaccine
Support programmes help prevent weight gain in women
A load of hot air
Guest Editorial

New and emerging therapies in Type 2 diabetes

by Dr. Giridhar Tarigopula & Professor Melanie J Davies

Dr Giridhar Tarigopula and Professor Melanie Davies, University Hospitals Leicester NHS Trust provide a review of the new drugs available for treating Type 2 diabetes and a look at what's on the horizon. 

Read more »

Diabetes

Pioglitazone plus exenatide brings more benefit to patients

Reporting from the American Diabetes Association (ADA) annual meeting, Orlando

by Thomas R Collins

Read more »

Hopes grow for artificial pancreas

by Thomas R Collins

These devices can control insulin pumps and automate some degree in the near-term.  And then we have visions to become more and more automated.

Read more »

Gastroenterology

IBD - Chemokine Inhibitor shows promise

Part II of reports from Digestive Disease Week (DDW) meeting, New Orleans

by Bruce Sylvester

At the end of the maintenance phase, all patients stopped assigned therapy and were followed for an additional four weeks.

Read more »

Modest result for new monoclonal antibody

by Bruce Sylvester

The primary endpoint was clinical response at the end of the eight-week period.

Read more »

Psychiatry

Clear take-home messages from ECNP

Reporting from the European College of Neuropsychopharmacology (ECNP) meeting, Amsterdam

Clear take-home messages from ECNP

In the field of brain disorders, the development of good biomarkers can enhance the possibilities for early diagnostics and the measurement of treatment effects.

Read more »

Catching multiple sclerosis before it strikes

Catching multiple sclerosis before it strikes

'Those who will develop MS will show a different blood signature from those who will not.'

Read more »

Dermatology

UV-B treatment may improve psoriasis and vitamin D levels

by Peter Mas Mollinedo UV-B treatment may improve psoriasis and vitamin D levels

'At the end of the study, all patients in the treatment group were vitamin D sufficient, but 75% of the control group had vitamin D insufficiency [serum 25(OH)D level of less than 20 nanograms per mililitre].'

Read more »

Women who drink beer more likely to develop psoriasis

by Peter Mas Mollinedo

Non-light beer was the only alcoholic beverage that increased the risk for psoriasis, suggesting that certain non-alcoholic components of beer, which are not found in wine or liquor, may play an important role in new-onset psoriasis.

Read more »

Palliative Care

Inadequate access to opioid-based pain relief is a human rights issue for cancer patients

Reporting from the European Association of Palliative Care (EAPC) meeting, Glasgow

by Samuel Peters

This is an issue of cancer patients' human rights, and it's not only a legal imperative, but a moral imperative for the WHO and individual European countries to address the findings of our report.  Dr. Nathan Cherny

Read more »

Emerging Uses of FDA-Approved Drugs

Statin therapy related to reduction in cancer recurrence following prostatectomy

FDA Highlights

by Bruce Sylvester Statin therapy related to reduction in cancer recurrence following prostatectomy

Read more »

Unapproved use of quinine sulfate gets FDA warning

by Bruce Sylvester

Read more »

Naltrexone and Bupropion for lowering bodyweight

by Bruce Sylvester

Read more »

Ketamine in quick relief of depression in treatment-resistant bipolar disorder

by Bruce Sylvester

While several treatments for bipolar depression are currently FDA-approved, some patients do not respond.

Read more »

Emerging uses of EMEA-Approved Drugs

EU-US collaboration on confidentiality

EMEA Highlights

by Gary Finnegan

Read more »

World Health Matters

Privatising alcohol sales ‘will spark violence’

Sweden

by Gary Finnegan Privatising alcohol sales ‘will spark violence’

Read more »

Function found for Alzheimer’s protein

Australia

by Gary Finnegan Function found for Alzheimer’s protein

"It has long been known that amyloid precursor protein (APP) forms plaques in Alzheimer’s patients leading to brain cell death and, ultimately, dementia."

Read more »

Research links Huntingtin to Neurogenesis

France

by Gary Finnegan Research links Huntingtin to Neurogenesis

"Given the predominant neurological signs and striking neuronal death in HD, most studies on htt function have focused on adult neurons."

Read more »

Heart attacks jump in young Italian women

Italy

by Gary Finnegan Heart attacks jump in young Italian women

"The increase was 17.2% in men and 29.2% in women."

Read more »

The BIG FOUR Journals

Icatibant shows promise for treating hereditary Angioedema

The New England Journal of Medicine (NEJM)

by Bruce Sylvester Icatibant shows promise for treating hereditary Angioedema

Read more »

Rosiglitazone treatment shows increase in CV risks and death

Journal of the American Medical Association (JAMA)

by Bruce Sylvester

Read more »

Study shows promise for Hepatitis-E Vaccine

The Lancet

by Bruce Sylvester

Read more »

Support programmes help prevent weight gain in women

British Medical Journal (BMJ)

by Bruce Sylvester

Read more »

View from The Waiting Room

A load of hot air

by Steve Devrell

"The report goes on to say that climate change has the greatest change on the poorest people of the world, the very people who have contributed least to its causes."

Read more »

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